Guillain-Barré (gee-YAH-buh-RAY) syndrome is a rare disorder in which your body's immune system attacks your nerves. Weakness and tingling in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing your whole body. In its most severe form Guillain-Barré syndrome is a medical emergency. Most people with the condition must be hospitalized to receive treatment.

The exact cause of Guillain-Barré syndrome is unknown. But it is often preceded by an infectious illness such as a respiratory infection or the stomach flu. There's no known cure for Guillain-Barré syndrome, but several treatments can ease symptoms and reduce the duration of the illness. Most people recover from Guillain-Barré syndrome, though some may experience lingering effects from it, such as weakness, numbness or fatigue.